PreparationofPoly(ethylene-co-acrylicacid)GraftedwithAliphatic QuaternaryAmmoniumSaltsasAntibacterialPolymers

저자

고*성

게재저널

Bulletin of the Korean Chemical Society

키워드

Antibacterialpolymer,Steglichesteri？cation,Quaternaryammoniumssalts,Poly(ethylene-co-acrylicacid)copolymer,Thermaldecomposition,Grafting,Electrospinning

개요

Toimprovetheantibacterialperformanceofpoly(ethylene-co-acrylicacid)(PEAA)copolymer,aliphatic quaternaryammoniumsalts(QASs)wasgraftedintoPEAAcopolymersviaaSteglichesteri？cationreac-tionusingN,N0-dicyclohexylcarbodiimide(DCC)asadehydratingagent.Thepolymersweresynthesized usingdodecyldimethylhydroxyethylammoniumchloride(DDHAC),whichwaspreparedbyquaterniza-tionofdimethylethanolamine(DMEA)with1-chlorododecane.Thesepolymerseffectivelyinhibitedthe growthofmicroorganismsduetotheirhydrophobicchains,whichwereboundtoPEAAcopolymers.The obtainedPEAA-g-DDHAC(PGD)wasinvestigatedbyattenuatedtotalre？ectance-Fouriertransform infraredspectroscopy(ATR-FTIR),protonnuclearmagneticresonance( 1 HNMR),thermogravimetric analysis(TGA),differentialscanningcalorimetry(DSC),andantibacterialtests.Theresultsshowedthat theantibacterialeffectsofPGDsweresigni？cantlyimprovedbyalkylgrafting,andthisimprovement dependedonreactiontemperature.Thehighestantibacterialactivitywasobservedforpolymerssynthe-sizedat135CagainstGram-positiveStaphylococcusaureusandGram-negativeEscherichiacoli.Their decompositionratewasacceleratedasthetemperatureincreasedabove165Cbecauseofthethermal decompositionofDDHAC.

첨부파일

• PreparationofPoly(ethylene-co-acrylicacid)GraftedwithAliphatic QuaternaryAmmoniumSaltsasAntibacterialPolymers.pdf [892,637 byte]

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